Poner a alguien de los nervios o irritarlo muchísimo.
To make someone extremely annoyed or irritated.
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See how the word “sacar de quicio” is used in sentences
El ruido constante me saca de quicio. — The constant noise drives me up the wall.
¿Por qué lo sacas siempre de quicio? — Why do you always drive him up the wall?
Por favor, deja de hablar; me estás sacando de quicio. — Please stop talking; you’re driving me up the wall.
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