Estropearlo todo por completo; informal.
To spoil everything badly; informal.
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See how the word “echarlo todo a perder” is used in sentences
Conseguí echarlo todo a perder. — I managed to screw everything up.
No lo eches todo a perder en tu primer día. — Don't screw everything up on your first day.
Un correo descuidado puede echarlo todo a perder. — One careless email can screw everything up.
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