Intentarlo no ayudará; es inútil.
Trying will not help; it is pointless.
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See how the word “no sirve de nada” is used in sentences
No sirve de nada discutir con él. — It's no use arguing with him.
Lo intentamos tres veces, pero no sirve de nada. — We tried three times, but it's no use.
No sirve de nada, la tienda cerró hace una hora. — It's no use, the shop closed an hour ago.
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