La causa più importante di qualcosa.
The most important cause of something.
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See how the word “motivo principale” is used in sentences
Il motivo principale per cui me ne sono andato era il rumore. — The main reason I left was the noise.
I soldi non erano il motivo principale del trasloco. — Money wasn't the main reason for the move.
Qual è il motivo principale per cui sei di nuovo in ritardo? — What's the main reason you're late again?
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